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Acetylsalicylic acid, better known as aspirin, is a mixed-function organic compound that offers excellent anti-rheumatic, anti-febrile and analgesic properties. In 1829, pharmacist H. Leroux was the first to isolate salicin from the bark of the willow plant. Later, in 1859, the German chemist Kolbe synthesized salicylic acid in his laboratory. However, this compound had unpleasant effects, such as stomach irritation. It was then that, in 1897, the pharmacist Felix Hoffman obtained acetylsalicylic acid, by carrying out a reaction between salicylic acid and acetic anhydride. Since then, this compound has been used to treat headaches, rheumatic fever and other ailments.
